Cirrhosis Surveillance Protocol
Based on recommendations from the British Society of Gastroenterology (BSG) and National Institute for Health and Care Excellence (NICE), simplified into:
👉 what you actually need to organise in clinic or on discharge
👉 not long guideline documents
Because once a patient has cirrhosis, your job changes from:
❌ “treat the liver disease”
to
✅ “prevent complications and detect cancer early”
Surveillance is what prevents deaths.
✅ Why surveillance matters
Cirrhosis patients are at risk of:
- Hepatocellular carcinoma (HCC)
- Variceal bleeding
- Ascites/SBP
- Encephalopathy
- Renal failure
Many of these are:
👉 silent until late
So we screen regularly.
✅ First principle
Think:
Every cirrhosis patient needs routine surveillance, even if they feel well.
Normal symptoms ≠ low risk.
🔴 1. HCC (liver cancer) surveillance – MOST IMPORTANT
This is the one you must never forget.
Cirrhosis = high HCC risk.
Early cancer is treatable.
Late cancer isn’t.
Who needs it?
👉 ALL patients with cirrhosis
(regardless of cause: alcohol, MASLD, hep B/C, autoimmune, etc.)
What to do?
Every 6 months:
- Liver ultrasound
- AFP blood test (optional but commonly used)
That’s it.
Simple.
Why 6 months?
Because:
- cancers grow fast
- yearly is too late
- 3 months unnecessary
So:
👉 6 months is the standard interval
Practical tip
When discharging:
👉 always check “next ultrasound booked?”
Very commonly missed.
🔴 2. Variceal surveillance (portal hypertension)
Prevents catastrophic bleeds.
Who needs OGD?
At diagnosis of cirrhosis:
👉 baseline OGD to look for varices
Then:
No varices
Repeat every 2–3 years
Small varices
Repeat every 1–2 years
Large varices
Start:
- non-selective beta blocker (carvedilol/propranolol)
OR - band ligation
No routine surveillance only — needs treatment.
Practical ward thinking
If you see:
“Cirrhosis – never scoped”
👉 they need OGD referral
🟡 3. Routine blood monitoring
Done regularly in clinic/GP.
Usually every 6–12 months.
Check:
- FBC
- U&E
- LFTs
- INR
- Albumin
Why?
Helps detect:
- worsening synthetic function
- decompensation
- renal issues
Trends matter more than single results.
🟡 4. Vaccinations (often forgotten)
All cirrhosis patients should have:
- Hep A
- Hep B
- Flu
- Pneumococcal
Because infection risk is higher and outcomes worse.
Easy win. Often missed.
🟡 5. Lifestyle + prevention
Simple but important.
Advise:
- alcohol cessation
- weight loss (MASLD)
- diabetes control
- avoid NSAIDs
- careful with nephrotoxic drugs
Prevents decompensation.
🔴 6. Watch for decompensation
Surveillance isn’t just tests — it’s recognising deterioration.
Red flags
- Ascites
- Encephalopathy
- GI bleeding
- Jaundice
- AKI
- Recurrent admissions
If present:
👉 urgent hepatology review
Not routine follow-up.
✅ Practical ward/clinic scenarios
Scenario 1
Stable alcoholic cirrhosis
→ 6-monthly US ± AFP
→ OGD schedule
Scenario 2
No varices on first OGD
→ repeat in 2–3 years
Scenario 3
Large varices found
→ beta blocker/banding
→ not just surveillance
Scenario 4
Missed ultrasound for 2 years
→ rebook urgently
Scenario 5
New ascites
→ decompensation
→ admission/workup, not routine clinic
✅ What juniors should check on ward round
For every cirrhosis patient, ask:
- Last ultrasound?
- Last OGD?
- On beta blocker?
- Vaccinated?
- Any decompensation?
If you check these five things, you’re doing good hepatology care.
❌ Common junior mistakes
- Forgetting HCC surveillance
- Thinking “they look well so no scan needed”
- Not arranging OGD
- Ignoring vaccinations
- Missing early decompensation
- Discharging without follow-up booked
Most harm is from missed follow-up, not missed drugs.
✅ Simple memory rule
Cirrhosis = 3 things to remember
👉 Scan every 6 months
👉 Scope for varices
👉 Monitor bloods
Everything else is secondary.
✅ Take-home concept
Cirrhosis care is proactive, not reactive.
Regular surveillance prevents bleeds and cancer.
If you only remember ultrasound every 6 months, you’ll already save lives.
